League One leaders Leicester City have been drawn away to Rotherham United in the Northern Section Quarter-Finals of the Johnstone's Paint Trophy.
Scunthorpe United, who trail the Foxes by three points, also face League Two opponents - they host Rochdale.
Dagenham and Redbridge, second in League Two, travel to fourth-placed Shrewsbury in the southern section.
And the basement's bottom two sides, Bournemouth and Luton, face League One opposition in Colchester and Walsall.
Johnstone's Paint Trophy, Quarter-Finals draw
Northern Section Rotherham United v Leicester City Tranmere Rovers v Morecambe Darlington v Bury Scunthorpe United v Rochdale
Southern Section Shrewsbury Town v Dagenham and Redbridge Brighton v Swindon Town Walsall v Luton Town Bournemouth v Colchester United
Ties to be played w/c 3 November
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