Miles Benjamin scored two of Warriors' five tries against London Welsh
Worcester held off a second-half London Welsh fightback to round off their home Championship fixtures with victory.
After Andy Goode and Gordon Ross exchanged early penalties, Worcester took complete control.
Tries from Kai Horstman, Goode, Marcel Garvey and Miles Benjamin helped the hosts to a 32-3 half-time lead.
Benjamin's second converted try made it 39-3, before the Exiles fought back with tries from James Lewis (2), Liam Gibson and Josh Drauniniu.
Worcester head coach Richard Hill told BBC Hereford and Worcester: "It was excellent but it was just disappointing that we conceded the tries towards the end, but they are dangerous.
"London Welsh in the end just threw it around from anywhere and attacked from deep, as we saw.
"They don't normally do that in the first 20 minutes, but they can very dangerous if they do that as they are a good side.
"It just shows you if they have the confidence to throw it from deep and we have just relaxed a little bit in defence that can happen and they scored some very good tries from deep."
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