Great Britain has named a 47-person team for the event which is the biggest Paralympic event ahead of the 2008 Beijing Games.

The GB team features some familiar faces as well as some new talents who will be aiming to make a big impression.

BBC Sport's Elizabeth Hudson looks at some of the Britons who will be chasing medals in Assen.

Name: Sophie Hancock
Age: 19
Events: F40 (Dwarf) Discus and Shot

Hancock has been performing well in both her events this year

The Bolton teenager emerged onto the international scene last year and won a surprise silver in the shot at the Open European Championships in Espoo, Finland.

This year, she had a disappointing time at the Paralympic World Cup, finishing only fourth behind Morocco's Laila El Garaa, compatriot Kim Minett and Petra Hommen.

But a lot of her work has been concentrated on the discus, where she has a real chance of a medal in Assen.

She set a new world best of 20m in the event at the recent UK Throws Fest in Birmingham and will be hoping to carry that sort of form into the event.

Name: Libby Clegg
Age: 16
Events: T12 (Blind/VI)100 and 200m

The visually impaired Scottish sprinter is one of the youngest members of the GB team in Assen and will be making her senior international debut.

Based in Edinburgh, where she attends the Royal Blind School, she has enjoyed a successful season so far, beating her personal bests by over a second in both sprint events.

Her guide runner will be former international athlete Lincoln Asquith who she has been working with regularly this season.

Only four athletes make it to the final in both of her events, which would be a lot to ask at her first major championship.

But the next four fastest make it to the B final, which will be the target for the talented teenager.

Name: Ben Rushgrove
Age: 18
Events: T36 (CP)100 and 200m, 4x100m relay

Rushgrove has put in some good displays this year

Rushgrove has gone from strength to strength over the past 12 months and he will be hoping to continue his progress in Assen.

Last year in Espoo, he was seventh in the 100m and sixth in the 200m but he has already improved his personal bests in both sprint events this year, taking almost a second off his 200m mark.

In June he was second to Athens bronze medallist Graeme Ballard at the CP Sport National Championships but set am under-20 best of 26.10 seconds in the 200m.

The final will again be a realistic aim but he could be a dark horse for an medal if he comes near his PB.

A former pupil at Treloar College in Hampshire, he will begin a foundation degree in Sports Performance at the University of Bath in October.

Name: John McFall
Age: 25
Events: T42 (Amputee) 100 and 200m

2006 has already been an eventful year for the Cardiff-based athlete after he had his prosthetic running leg stolen from his car in January before it was later returned.

He has already improved his 100m time from 13.39 seconds to 12.8 while in the 200m (his favoured event), his best time is now 26.02 seconds and he is targeting the world record of 25.75.

His biggest rivals will be German duo Wojitek Czyz and Heinrich Popow, Frenchman Clavel Kayitare and Japan's Atsushi Yamamoto.

At Espoo last year, he claimed a bronze in the 200m and was fourth in the 100m and is hoping for more this time.

"I'm confident of winning medals in both events," he told BBC Sport. "What colour they are depends on how well I perform but gold is certainly in my sights."

Name: David Weir
Age: 27
Events: T54 (Wheelchair) 100, 200, 400, 800, 1500m and Marathon

Weir claimed a superb victory over 1500m in Helsinki in August

Britain's wheelchair racing star goes to Assen on the back of some superb victories and world records already this year.

After winning the London Marathon earlier this year, his track season has been equally successful with three golds at the Paralympic World Cup over 100, 200 and 1500m, victory over 800m at the London Grand Prix and European gold in the 1500m in Helsinki.

He broke the world 200 and 400m records in one meeting in Switzerland in May and improved his 400m mark further at the Swiss Open in his last meeting before Assen.

Weir has been focussing a lot of his training on the longer distances (800 and 1500m) this year and Assen will be the first big test of how he is faring against the world's best distance specialists.