Sheffield United are waiting to hear the full extent of striker Darius Henderson's knee injury.
The 27-year-old had a scan on the injured knee on Tuesday after damaging ligaments in training and missed the Blades 1-1 draw with Coventry City.
"We don't know how bad it is, there was no one around him," Blades boss Kevin Blackwell told BBC Radio Sheffield.
"We lose [midfielder] Matthew Spring with ankle ligaments and then Henderson goes down."
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The loss of Henderson leaves the Blades short of options up front after selling John Stead to Ipswich this week.
But Blackwell remains optimistic: "These things happen in football, you've got to be big enough and brave enough to carry on."
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