The pair came through the full 90 minutes on Tuesday
Leicester City defenders Joe Mattock and Patrick Kisnorbo returned to action in a 2-1 reserve win over West Brom.
Kisnorbo, 27, has been sidelined since picking up a knee injury against Sheffield Wednesday in April.
In August, England under-21's Mattock was stretchered off in the Carling Cup against Stockport with an ankle injury.
Reserve team manager Gerry Taggart told the club website: "Both Patrick and Joe came through the full 90 minutes, which will do them the world of good."
He added: "It was a physical contest and they certainly didn't shirk any challenges."
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