Slovenia, who finished runners-up in Northern Ireland's World Cup qualifying group, will provide a stern opening test.
Northern Ireland lost 2-0 in Slovenia in the opening meeting between sides in the qualifiers before Worthington's side clinched a 1-0 victory in Belfast.
The Slovenians went on to beat Russia in the play-offs and secure a place at the finals in South Africa.
It is a tough group for Northern Ireland with Serbia and Italy also set to compete in South Africa.
Euro 2012, Group C qualifiers
Friday, 3 Sept 2010 - Slovenia v Northern Ireland
Friday, 8 October 2010 - Northern Ireland v Italy
Tuesday, 12 October 2010 - Faroe Islands v Northern Ireland
Friday, 25 March 2011 - Serbia v Northern Ireland
Tuesday, 29 March 2011 - Northern Ireland v Slovenia
Wednesday, 10 August 2011 - Northern Ireland v Faroe Islands
Friday, 2 September 2011 - Northern Ireland v Serbia
Tuesday, 6 September 2011 - Estonia v Northern Ireland
Friday, 7 October 2011 - Northern Ireland v Estonia
Tuesday, 11 October 2011 - Italy v Northern Ireland
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