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Episode details

World Service,23 Oct 2025,10 mins

GLP-1: A breakthrough for diabetes and obesity

Witness History

Available for over a year

In the 1980s, scientists made a discovery that would eventually lead to the development of drugs now used worldwide to treat diabetes and to help people manage obesity through weight loss injections. One of the key scientists behind this breakthrough was Svetlana Mojsov. She discovered that a hormone called GLP-1 (glucagon-like peptide-1) plays an important role in how our bodies respond to food. Svetlana’s work laid the foundation for a drug company to develop treatments based on GLP-1 — first for type 2 diabetes, and later for weight loss. She tells Gill Kearsley her story. Eye-witness accounts brought to life by archive. Witness History is for those fascinated by the past. We take you to the events that have shaped our world through the eyes of the people who were there. For nine minutes every day, we take you back in time and all over the world, to examine wars, coups, scientific discoveries, cultural moments and much more. Recent episodes explore everything from the death of Adolf Hitler, the first spacewalk and the making of the movie Jaws, to celebrity tortoise Lonesome George, the Kobe earthquake and the invention of superglue. We look at the lives of some of the most famous leaders, artists, scientists and personalities in history, including: Eva Peron – Argentina’s Evita; President Ronald Reagan and his famous ‘tear down this wall’ speech; Thomas Keneally on why he wrote Schindler’s List; and Jacques Derrida, France’s ‘rock star’ philosopher. You can learn all about fascinating and surprising stories, such as the civil rights swimming protest; the disastrous D-Day rehearsal; and the death of one of the world’s oldest languages. (Photo: Injection pens. Credit: Carsten Snejbjerg/Bloomberg via Getty Images)

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