Cell differentiation
Newly formed cells are undifferentiated. That is, they are stem cellA cell found in foetuses, embryos and some adult tissues that can give rise to a wide range of other cells. and have not yet become specialisedA cell that has become differentiated to carry out a particular function, eg red blood cell. in a process called cell differentiationWhen an unspecialised cell becomes a more specialised cell type..
Large, multicellularHaving more than one cell. organisms like humans are made from many different cell types. There are over 200 specialised cells in our bodies. So, stem cells must differentiate so that they develop the features that enable them to fulfil their specific roles. Once they have specialised, they are unable to change into other cell types.
Specialised cells in animals
| Cells of the… | Specialised to… |
| Circulatory system | Transport substances, defend the body, regulate temperature |
| Excretory system | Remove waste products and unwanted substances, regulate the water content of the body |
| Muscular system | Bring about movement |
| Nervous system | Respond to internal and external stimuli and conditions, carry messages for the body to work as a coordinated whole |
| Respiratory system | Deliver oxygen for respiration and remove waste |
| Reproductive system | Bring about fertilisation to produce new offspring |
| Skeletal system | Bring about movement, support and protect internal structures, produce blood cells, store and release calcium |
| Cells of the… | Circulatory system |
|---|---|
| Specialised to… | Transport substances, defend the body, regulate temperature |
| Cells of the… | Excretory system |
|---|---|
| Specialised to… | Remove waste products and unwanted substances, regulate the water content of the body |
| Cells of the… | Muscular system |
|---|---|
| Specialised to… | Bring about movement |
| Cells of the… | Nervous system |
|---|---|
| Specialised to… | Respond to internal and external stimuli and conditions, carry messages for the body to work as a coordinated whole |
| Cells of the… | Respiratory system |
|---|---|
| Specialised to… | Deliver oxygen for respiration and remove waste |
| Cells of the… | Reproductive system |
|---|---|
| Specialised to… | Bring about fertilisation to produce new offspring |
| Cells of the… | Skeletal system |
|---|---|
| Specialised to… | Bring about movement, support and protect internal structures, produce blood cells, store and release calcium |
Specialised cells in plants
| Cells of the... | Specialised to... | |
| Leaf | Palisade mesophyll | Carry out photosynthesis |
| Spongy mesophyll | Allow gases to circulate for the exchange of gases between the leaf and the environment, carry out some photosynthesis | |
| Guard cells | Open and close to control the exchange of gases – carbon dioxide, water vapour and oxygen | |
| Phloem | Sieve tubes | Transport products of photosynthesis, including sugars and amino acids, from the leaf to where they are needed |
| Companion cells | Provide the energy required for transporting substances in sieve tubes | |
| Xylem | Xylem vessels | Transport water and dissolved minerals from the roots, up the plant |
| Growing points | Meristem | Produce new cells as they divide |
| Leaf | |
|---|---|
| Cells of the... | Palisade mesophyll |
| Specialised to... | Carry out photosynthesis |
| Cells of the... | Spongy mesophyll |
|---|---|
| Specialised to... | Allow gases to circulate for the exchange of gases between the leaf and the environment, carry out some photosynthesis |
| Cells of the... | Guard cells |
|---|---|
| Specialised to... | Open and close to control the exchange of gases – carbon dioxide, water vapour and oxygen |
| Phloem | |
|---|---|
| Cells of the... | Sieve tubes |
| Specialised to... | Transport products of photosynthesis, including sugars and amino acids, from the leaf to where they are needed |
| Cells of the... | Companion cells |
|---|---|
| Specialised to... | Provide the energy required for transporting substances in sieve tubes |
| Xylem | |
|---|---|
| Cells of the... | Xylem vessels |
| Specialised to... | Transport water and dissolved minerals from the roots, up the plant |
| Growing points | |
|---|---|
| Cells of the... | Meristem |
| Specialised to... | Produce new cells as they divide |
Stem cells
Find out where stem cells come from and how they are used in humans and plants
Stem cells are cells that have not undergone differentiation. An embryoAn organism in the early stages of development. develops from a fertilised egg. Cells at early stages in the development of the embryo are stem cells.
If cells are removed from the embryo – called embryonic stem cellA type of stem cell found in the embryo, capable of dividing into almost any cell type. – they will differentiate into any cell type.
Some stem cells remain in the bodies of adults – adult stem cellA type of stem cell found in specific locations in adults. Adult stem cells can only differentiate into a limited number of related cell types..
Adult stem cells are found in limited numbers at certain locations in the body, including the:
- brain
- eyes
- blood
- heart
- liver
- bone marrow
- skin
- muscle
Adult stem cells can differentiate into related cell types only, for example, bone marrowSoft tissue found inside bones that produces new blood cells. cells can differentiate into blood cells and cells of the immune systemThe body's defence system against entry of any foreign body, including pathogens and agents such as pollen grains. The role of the immune system is to prevent disease. but not other cell types.
Stem cells in plants
Cell division in plants occurs in regions called meristemA region in plant shoots and roots in which cells are dividing, and so are undergoing mitosis..
Cells of the meristem can differentiate to produce all types of plant cells at any time during the life of the plant.
The main meristems are close to the tip of the shoot, and the tip of the root.
In a growing shoot, new cells are being produced continuously near the tip. As the cells become older, further away from the tip, they become differentiated – they enlarge and develop vacuoleA space within the cytoplasm of plant cells that contains cell sap..
Learn more about stem cells with Dr Alex Lathbridge.
Listen to the full series on BBC Sounds.
In this podcast, learn the key facts about stem cells. Listen to the full series on BBC Sounds.
More guides on this topic
- States of matter - AQA Synergy
- States of matter: interactive activity - AQA Synergy
- Atomic structure - AQA Synergy
- Cells in animals and plants - AQA Synergy
- Transport into and out of cells - AQA Synergy
- Mitosis: interactive activity - AQA Synergy
- Waves - AQA Synergy
- Sample exam questions - building blocks - AQA Synergy