Genetic inheritance - part one - EdexcelFamily trees

Mutations can cause a permanent change in the DNA of an organism. In the 19th century, Gregor Mendel determined rules to explain genetic inheritance using pea plants. Genetic crosses using Punnett squares show how likely offspring are to inherit characteristics from their parents.

Part ofBiology (Single Science)Genetics

Family trees

Pedigree analysis

Doctors can use a to show how genetic disorders are inherited in a family. They can use this to work out the that someone in a family will inherit a condition. A pedigree analysis is usually undertaken if families are referred to a genetic counsellor following the birth of an affected child.

A visual to show a pedigree analysis chart that can help people find out about inherited disorders and diseases.
Figure caption,
A pedigree analysis chart showing the offspring of an affected male and unaffected female

The pedigree analysis chart is used to show the relationship within an extended family. Males are indicated by the square shape and females are represented by circles. Affected individuals are red and unaffected are blue. Horizontal lines between males and females show that they have produced children.

This analysis shows both male and female are affected, and every generation has affected individuals. There is one family group that has no affected parents or children, but the remaining two families have one affected parent and affected children too.