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1200 Andrew welcomes our guest for the programme: a personage with so many titles, it's hard to know where to start: scientist, writer, broadcaster, professor, Baroness and Director of the Royal Institute - it is, of course, Susan Greenfield.

1204 The Chancellor's flagship tax credit scheme to help poorer working families is in trouble yet again this morning. One of the most powerful committees in Parliament has released a report saying that for the second year running, gigantic overpayments have been made which families will struggle to repay. The government has form on this - in fact the systems for paying all sorts of credits and benefits seem to be awash with errors amounting to billions of pounds. Jenny asks whether the government needs some maths lessons?

1206 Jenny talks to the Conservative MP who's made a study of the affair, David Ruffley.
He says: "It's the system that's been overcomplicated, and it's been overcomplicated by Gordon Brown. All sensible outside observers and opposition politicians said at the time that people can't forecast a year in advance what their income will be. But particularly those on low pay who may have movements in and out of jobs. It was madness to begin with and this overcomplication is causing the overpayment."

1208 Andrew welcomes into the conversation Labour MP Sally Keeble, who's on the Treasury Select Committee.
She says:"There are improvements being made to it, and I completely agree that there's a need to improve it further. But if you say which is better, a low flat-rate system or a complex system which tries to target need and to achieve particular things - I prefer the second."

1215 What do these groups have in common: nurses, police officers, teachers, social workers and paramedics? They're all public sector workers who can get a hand-up onto the property ladder. John Prescott's department has spent hundreds of millions of pounds on subsidised homes for these so-called key workers. But some of the buildings are empty and stuck on the market. Laura's been to Cambridge, where some of the houses are being built, to find out why.

1220 You may have noticed this morning the record profits announced by Britain's biggest supermarket, Tesco: �2.2bn profit, a rise of 17% on the year. Now with over 1,000 stores nationwide, it accounts for a third of all our spending on groceries. This dominance has led critics to claim that it's pushing small shops out of business and forcing suppliers to accept lower prices. The Competition Commission is set to launch an inquiry into British supermarkets to address these concerns. It will be the third such investigation into supermarkets since 1999. Tesco is also facing accusations that it's built up a portfolio of land not for its own use but to prevent competitors from getting access to it, something Tesco denies. Jenny asks Kevin Hawkins of the British Retail Consortium whether the criticisms of Tesco were fair.

1222 Andrew talks to someone who's not so wild about this morning's announcement, the Liberal Democrat MP Greg Mulholland, who's a member of the all-party parliamentary group on small shops.

1225 Your questions and emails for Baroness Greenfield.

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