Richie Pugh takes over from Dafydd Jones at open-side flanker, Ken Owens replaces Rees, Tavis Knoyle is scrum-half instead of Martin Roberts, Rob Higgitt fills Davies' centre spot while Stoddart fills Mark Jones' wing spot.
Stoddart proved his fitness by playing 20 minutes of Llanelli RFC's 32-32 Principality Premiership clash at Aberavon at the weekend.
Regan King and Rhys Thomas remain long-term injuries.
Connacht have slipped to three straight defeats in the Magners League, while Scarlets have won their last three games in all competitions.
The Scarlets' only victory in their last five visits to Ireland was 17-14 in this fixture last season, while Connacht have won just one of their last six matches against the Llanelli-based side, 20-18 at the Sportsground in January last year.
Connacht: tbc
Scarlets: Daniel Evans; Morgan Stoddart, Sean Lamont, Rob Higgitt, Lee Williams; Rhys Priestland, Tavis Knoyle; Iestyn Thomas, Ken Owens, Deacon Manu, Vernon Cooper, Damien Welch, Simon Easterby, Richie Pugh, David Lyons. Replacements: Phil John, Emyr Phillips, Aaron Shingler, Josh Turnbull, Gareth Davies, Dan Newton, Gareth Maule.
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