Oxford United's comfortable pre-season win at Maidenhead was blighted by injuries to keeper Jake Cole and defender Luke Foster.
Cole had to go off with a groin injury after 17 minutes. Physio Neil Sullivan told BBC Radio Oxford: "He felt it and we didn't want to take chances."
Foster was substituted with a broken nose early in the second half.
Two goals from Lewis Haldane and a penalty from Jamie Guy gave Oxford a 3-1 win.
Maidenhead's consolation goal game in injury time from substitute Ryan Hazell.
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