Central defender Liam Ridgewell has undergone an operation on the broken leg he suffered in Birmingham's 1-1 draw with Plymouth on Easter Monday.
The 24-year-old will miss the the end of the season after being injured in a challenge with Argyle striker Jamie Mackie midway through the first half.
Blues boss Alex McLeish told the club's website: "It wasn't anybody's fault, but suffice to say his season is over."
Meanwhile the Blues have also appealed against keeper Maik Taylor's dismissal.
Taylor was sent off after 22 minutes after being adjudged to have brought down Jamie Mackie for a penalty.
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