Basle 2-0 Middlesbrough: David Degen causes a number of problems for Boro and is booked for diving after 29 minutes

Shortly before half-time a speculative shot by Matias Delgado bounces over Mark Schwarzer and into the net

Boro are left reeling moments later when Degen emphatically finishes to give Basle a 2-0 lead at the interval

No further goals are scored leaving Middlesbrough boss Steve McClaren with plenty to ponder ahead of the second leg

Levski Sofia 1-3 Schalke: Daniel Borimirov gets the hosts off to a great start when he robs Hamit Altintop to score

With 35 minutes played, English referee Mike Riley dismisses Levski's C�dric Bardon for a second bookable offence

Schalke's greater numbers take their toll on the Bulgarians' defence and Gustavo Varela equalises shortly after half-time

They then go in front midway through the second half when Brazilian midfielder Lincoln finishes a neat move

The scoring is completed by Gerald Asamoah who is the first to react after Christian Poulsen's header hits the post

Rapid Bucharest 1-1 Steaua Bucharest: Banel Nicolita nets after just five minutes for the visitors in the Romanian derby

Rapid draw level in the 50th minute when Viorel Moldovan prods home after goalkeeper Carlos Alberto Fernandes' error

Sevilla 4-1 Zenit St Petersburg: A pass from Adriano Correia is headed home by Javier Saviola as the hosts take the lead

On the stroke of half-time, Aleksandr Kerzhakov equalises for Zenit after combining well with Andrei Arshavin

Second-half goals from Mart�, Saviola and Adriano put the Spanish side in a very strong position ahead of the return leg