Cambridge United sank Burton Albion to end the Blue Square Premier leaders' 17-game unbeaten league run.
The U's dominated possession from the start but had to wait until the second half for Scott Rendell to break the deadlock from Courtney Pitt's cross.
Jai Reason's clever pass set up Robbie Willmott to make it 2-0 as Cambridge continued to dominate.
Burton's miserable day was completed when Martin Butler was shown a straight red card for a tackle on Danny Potter.
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Cambridge Utd:
Potter, Gleeson, Bolland, Hatswell, Tonkin, Willmott (Parkinson 86), Carden, Reason, Pitt, Rendell, Holroyd. Subs Not Used: Grundy, McMahon, Challinor, Coulson.
Goals: Rendell 55, Willmott 76.
Burton Albion:
Poole, Austin, James, Buxton, Webster, Corbett (Pearson 60), Simpson, McGrath, Gilroy (Goodfellow 73), Harrad, Butler. Subs Not Used: Deeney, Stride, Holmes.
Sent Off: Butler (82).
Booked: Harrad, McGrath.
Att: 4,377
Ref: S Beck (Essex).
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