Mark Convery late long-range leveller earned Cambridge a point as both sides were reduced to ten men at Crawley.
Jon-Paul Pittman put Crawley ahead on the half-hour when he beat two defenders and score from close range.
Cambridge levelled after the break when Lee McEvilly scored from the spot after being fouled by Chris Giles.
Thomas Pinault's penalty put Crawley back in front, but Convery had the last word after Cambridge's Ben Farrell and Crawley's Sam Rents both saw red.
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Sent Off: Rents (82).
Booked: Pinault, Bulman, Stevens.
Goals: Pittman 30, Pinault 61 pen.
Sent Off: Farrell (76).
Booked: Farrell, Coulson, Gleeson, Convery.
Goals: McEvilly 54 pen, Convery 90.
Att: 1,570
Ref: Ian Cooper (Rochester).
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