Jefferson Louis proved a handful for the Salisbury defence
Wrexham fought back from going a goal behind at Salisbury to crush the overnight Blue Square Premier leaders at the Raymond McEnhill Stadium.
Andrew Sandell's 10th-minute free-kick gave Salisbury an early advantage.
But Shaun Whalley's classy curler put Wrexham level before half-time, before Jefferson Louis struck twice with a header and strong drive into the box.
Whalley capped off a fine comeback with his second in injury time, his 30-yard shot taking a deflection on its way in.
Wrexham manager Brian Little: "Fair play to Salisbury, in those first 20 minutes they would have got a goal against anyone, they really came out of the blocks and their energy level was unbelievable.
"On a day like this it didn't surprise me that they tired a little, you could see it going out of them and thankfully we were only a goal down.
"We gradually took over the game, and when we got out first goal we were always the better side."
Wrexham: Ward, Spender, Kempson, Steve Evans, Tremarco, Baynes (Gareth Evans 85), Nathaniel Brown (Mackin 8), Kearney, Whalley, Simon Brown, Louis (Aiston 82). Subs Not Used: Smith, Anthony Williams.
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