A late brace from Forest Green's Adriano Rigoglioso condemned Weymouth to their first defeat of the season.
Jonathan Smith fired low from 18 yards to open the scoring but with 20 minutes remaining Weymouth drew level thanks to Scott Doe's powerful right-foot drive.
Rigoglioso stroked home to put Forest Green back in front and he sealed the points with a 30-yard free-kick.
Lee Fowler put the gloss on Forest Green's performance as he converted Kaid Mohamed's through-ball.
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