Middlesbrough 0-2 Manchester United: Struggling Boro start well but have their resistance broken in the 25th minute when a loose ball runs across the edge of the area and Ryan Giggs rifles home a first-time shot
Sadly for Boro, a second goal arrives soon after the break when Wayne Rooney finds Ji-Sung Park who loses David Wheater before firing home
No further goals materialise as Sir Alex Ferguson's side cruise to a win that leaves them six points clear at the top, while the hosts stay in the bottom three
Chelsea 3-1 Fulham: Blues manager Guus Hiddink opts to pair Didier Drogba and Nicolas Anelka together up front and they combine for the latter to score a first-minute goal
Their lead disappears three minutes later when Norwegian striker Erik Nevland fires a fine shot across Petr Cech to bring the sides level in the west London derby
With 10 minutes played a low cross from Drogba evades Fulham defender John Pantsil and finds Florent Malouda who fires home to make it 2-1 as the thrilling start to the match continues
After creating the first two, Drogba gets one of his own to seal victory after a ball from Anelka puts him through on Mark Schwarzer's goal
Portsmouth 0-3 Arsenal: With several key players rested, the Gunners make a good start and see Nicklas Bendtner's header give them the lead following a handling error by goalkeeper David James
Referee Lee Mason awards a penalty after a foul by Sean Davis on Andrey Arshavin, allowing the young Danish striker to register a second from the spot in the 41st minute
Shortly before the hour Arsenal have a third when Arshavin lays the ball back for Carlos Vela to shoot low past James from the edge of the penalty area
Stoke City 0-1 West Ham United: Diego Tristan's fantastic 20-yard free-kick in the latter stages of the first half proves to be enough for the Hammers to take all three points
Tottenham Hotspur 1-0 West Bromwich Albion: The north London club's quest for a European place receives a boost just before the break when Jermaine Jenas scores the only goal with a curling effort beyond Scott Carson
Manchester City 3-1 Blackburn Rovers: The visitors fail to clear their lines from a corner and the ball falls for Felipe Caicedo who prods home from the edge of the six-yard box shortly before the half hour
Mark Hughes' side have a second soon after thanks to Robinho whose first-time finish beats Paul Robinson from the edge of the penalty area
Elano finds himself on the scoresheet on the stroke of half-time after Gael Givet handballs to concede a penalty which the Brazilian converts
Blackburn have a consolation goal midway through the second half when Keith Andrews bundles home after Shay Given saves El-Hadji Diouf's penalty and the striker's follow-up
Wigan Athletic 0-0 Bolton Wanderers: Latics defender Titus Bramble does his best to prevent Kevin Davies from opening the scoring as the two clubs play out a goalless draw at the JJB Stadium
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