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Rafael Nadal beaten by Frances Tiafoe 6-4, 4-6, 6-4, 6-3
World number one Iga Swiatek beats Jule Niemeier 2-6 6-4 6-0
Swiatek will play Jessica Pegula who defeated Petra Kvitova 6-3 6-2
Cameron Norrie loses 6-4 6-4 6-4 to Andrey Rublev in last 16
Collins v Sabalenka followed by Cilic v Alcaraz in night session (midnight UK)
Day eight of final Grand Slam of year at Flushing Meadows
That's all from us for today.
You can read all about Frances Tiafoe's stunning win over Rafael Nadal here.
Today's stories from the US Open, including defeat for Britain's Cameron Norrie, can be found here.
And keep up to date with all the latest scores on this page.
Goodnight and catch you tomorrow!
Rafael Nadal has given his post-match press conference and says he does not know when he will next be in action following his US Open fourth round defeat by Frances Tiafoe.
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It's quarter-finals time on day nine of the 2022 US Open!
Up first on Arthur Ashe tomorrow is Italy's Matteo Berrettini up against Norway's Casper Ruud, before Tunisian Ons Jabeur's last-eight meeting with Australia's Ajla Tomljanovic follows that match.
American Coco Gauff and France's Caroline Garcia kick off the night session, before Australian Nick Kyrgios takes on Russia's Karen Khachanov.
Image source, Getty ImagesNever mind the choice of leader of the Conservative Party, only one vote result matters today.
To mark her expected retirement from tennis, we've been running a vote over the past two days on Serena Wiliams' top 10 moments and the results are officially in.
Coming in top with 20% of the selections was Williams winning the 2017 Australian Open to overtake Steffi Graf's Open era record of 22 Grand Slams in singles. And of course we later found out that she did this while eight weeks' pregnant.
That just pipped her defying racist boos to win the Indian Wells title in 2001 (19%) with her London 2012 Olympics gold medal in singles in third place, selected by 14% of participants.
Scroll to the bottom of this article for the full results.
The race to become the new men's world number one is well and truly ON.
Daniil Medvedev's defeat by Nick Kyrgios yesterday means the Russian will lose his top ranking at the end of the tournament.
Following his loss tonight, Rafael Nadal, with no points to defend after missing last year's US Open, is still in the driving seat as it stands.
But Carlos Alcaraz and Casper Ruud both now know a run to the final could see them become the new top ranked men's player!
Image source, Getty ImagesNadal 4-6 6-4 4-6 3-6 Tiafoe
With his fourth round victory over Rafael Nadal, Frances Tiafoe has:
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#bbctennis
Sulaimon Adelekan: With Nadal out, this is Nick Kyrgios's biggest chance to win a Grand slam.
Joe Gibney: Cameron Norrie will look at Rafael Nadal's result. and think opportunity missed.
ashic: Rafa made way too many mistakes today. His second serve strategy backfired big time. But what an incredible moment for Tiafoe
Alex Haworth: Nadal really doesn't like it indoors does he?
*Azarenka 5-7 2-0 Pliskova
Victoria Azarenka has struggled with break points tonight but she finally sees one stick, winning with a passing shot to go a break up in the second set.
We've got an intriguing last 16 tie on Louis Armstrong.
Nadal 4-6 6-4 4-6 3-6 Tiafoe
We will have to wait and see what Rafael Nadal's plans are for the rest of the season.
But two Grand Slam titles, and a 22-1 record at majors, represents a very good return indeed for a player who feared his career might be ended by injury in 2021.
Hopefully we'll get his thoughts from his press conference shortly.
Image source, Getty ImagesGlasspool/Heliovaara 3-6 7-6 (8-6) Kyrgios/Kokkinakis
On the Grandstand two match points on Nick Kyrgios' serve have just slipped by for the special Ks in a second-set tie break.
A double fault from Thanasi Kokkinakis hands Lloyd Glasspool and Harri Heliovaara the second set and we go to a decider.
A look up to the clouds though on this roofless court, and it seems very grey...
Nadal 4-6 6-4 4-6 3-6 Tiafoe
On how he felt at the end as he tried to close out the match, Tiafoe added:
"My legs were like cement when I went up at 4-3!
"I played great tennis today. I have to give [Nadal] the respect but I came out to win a tennis match in front of you guys."
And on facing Andrey Rublev next, he said:
"I am not thinking about my next match now.
"I'm just happy I won in front of my mum, my dad, my girlfriend and my team and to have them see what I did today."
Image source, Getty ImagesNadal 4-6 6-4 4-6 3-6 Tiafoe
Here is what Frances Tiafoe had to say following his win:
"I don't know what to say, I'm so happy. He's one of the greatest of all time and I played unbelievable tennis today.
"Something special happened today.
"Honestly when I first came on the scene I wasn't ready for it mentally and mature enough.
"I've been able to develop and I have great team around me. With you guys, it's been great."
Image source, Getty ImagesNadal 4-6 6-4 4-6 3-6 Tiafoe
We'll bring you what Frances Tiafoe had to say in his post-match interview shortly.
Who knows what we might learn from Rafael Nadal's press conference later. He disappeared for around nine minutes after losing the first set as he received a medical timeout, but he did not appear to be struggling physically following that break.
The 22-time Grand Slam winner had even broken for a 3-1 lead in that fourth set, before Tiafoe came storming back to take the biggest victory of his career.
Jonathan Jurejko
BBC Sport at Flushing Meadows
Fair to say the locals are happy about this one!
Acoustic waves puncture the Ashe roof as American fans jump to their feet in celebration.
Camera phones are flashing like it’s a disco.
Tiafoe is in bits.
Image source, BBC SportNadal 4-6 6-4 4-6 3-6 Tiafoe
It will be Russian ninth seed Andrey Rublev next for Frances Tiafoe, who will not fear anyone following this impressive victory.
Nadal 4-6 6-4 4-6 3-6 Tiafoe
Laura Robson
Former British number one at Flushing Meadows
I have to say I am so happy for Tiafoe. He's been building to a win like this for so long.
This is massive.
Nadal 4-6 6-4 4-6 3-6 Tiafoe
An emotional Tiafoe rests his head in his towel as he takes his seat, attempting to allow the gravity of his achievement to sink in.
It's his second major quarter-final - and his very first at his home Slam.
And he's secured it by beating the great Rafael Nadal in four sets.
Nadal 4-6 6-4 4-6 3-6 Tiafoe
Russell Fuller
Tennis correspondent at Flushing Meadows
Nadal is beaten in a Grand Slam in 2022.
A wonderful performance of performance and power from the 24-year-old, who is sobbing into his shirt
Nadal 4-6 6-4 4-6 3-6 Tiafoe
What an incredible performance from Frances Tiafoe!
He can't quite believe it.
The crowd erupt as the American heads round the net to shake hands with Rafael Nadal.
It's Nadal's first defeat at a Grand Slam this year. 22-1.
*Nadal 4-6 6-4 4-6 3-5 Tiafoe
A crashing forehand!
0-40!
Three match points for Frances Tiafoe!
