Roma's Brazilian keeper Alisson Becker couldn't keep out a sublime free-kick by Fred
Shakhtar Donetsk came from behind to beat Roma in the Champions League last-16 first leg thanks to a stunning free-kick by Brazil midfielder Fred.
Argentine striker Facundo Ferreyra, who did not play a minute for Newcastle during a season-long loan in 2014-15, struck to cancel out the opener by Roma's exciting Turkish winger Cengiz Under.
Then Fred, 24, who has been linked with a move to Premier League leaders Manchester City, curled his free-kick over the wall and into the top corner.
Shakhtar, who had defender Serhiy Kryvtsov stretchered off before half-time, travel to Rome for the second leg on Tuesday, 13 March (19:45 GMT).
Eusebio di Francesco's Roma, who are third in Serie A, impressed in the first half with former Manchester City striker Edin Dzeko linking up well with Under.
But Shakhtar, who have now won 12 of 15 games in Kharkiv where they play due to conflict in their eastern Ukraine home, were only denied a bigger lead by Roma goalkeeper Alisson Becker, who thwarted Marlos, Taison and Ferreyra in added time.
Shakhtar's Samba Boys shine
Shakhtar's players celebrate their comeback
It was -9C in Kharkiv but Shakhtar's Samba contingent shone like it was a balmy night in Sao Paulo.
Skipper Taison, playmaker Bernard, highly rated midfielder Fred and over-lapping full-back Ismaily - not to mention Brazil-born Ukraine international Marlos - played a big part in the hosts' win - registering 10 attempts on goal between them.
The reigning Ukrainian Premier League champions have a proud heritage of Brazilian imports; Fred is their 14th different player from that country to score in the Champions League. Only Porto with 21 have had more scorers from the South American nation in the competition's history.
This graphic shows how many times Taison, Bernard, Ismaily, Fred and Marlos touched the ball in Roma's half
Fred has made headlines in England recently with those strong rumours that Pep Guardiola covets his signature and his free-kick will ensure more attention.
But it was 5ft 5in playmaker Bernard who barely put a foot wrong, with 90% passing accuracy and more touches (73) than any team-mate.
Roma had hoped their own midfielder Radja Nainggolan would have an impact, but he struggled, only touching the ball 28 times - 45 times fewer than Bernard - and was subbed on 85 minutes.
The Italians had their own Brazilian saviour in shot-stopper Alisson, who made the key saves that mean they still have a chance to progress in Rome with an away goal in their favour.
Man of the match - Bernard (Shakhtar Donetsk)
Bernard (right) weighed in with three tackles, second highest for his team, and linked up smartly with countryman Ismaily on the left to find space
What they said
Shakhtar coach Paulo Fonseca said: "We didn't actually start the game too badly, and even created a good chance, but didn't have a player to poke the ball in. Later there was a problem with our positioning. Roma were aggressive while our lines were stretched. We sorted this after the break and that helped us win.
"The team performed well in the second half. It wasn't easy to keep up that pace after a long winter break. The only reason we didn't win by a bigger margin was a brilliant display from Roma's keeper."
Roma coach Eusebio Di Francesco: "My team has everything it takes to play 90 minutes at a high level so the mistakes we made are mental. I told the team to play the second half the way we played the first, but what I saw on the pitch is that team was happy to defend. We need to work on that.
"My team lacks the ability to maintain momentum and perform in spite of difficulties. We lost our concentration at 1-1. Shakhtar are a great side. We'll do everything to turn this around, but it'll be very difficult."
No place like adopted home for Shakhtar - the stats
Shakhtar have won all four of their home games in the tournament this season, their best such run since their last win over Roma in March 2011 (five straight wins). Indeed, the only other side to have won four home matches in this season's competition are Bayern Munich.
All three of Shakhtar Donetsk's knockout stage wins in the Champions League have been against Roma. Indeed, three of Roma's last five defeats in the competition's round of 16 have been against the Ukrainian side.
Shakhtar have now found the net at least twice in six consecutive home Champions League games - the joint-longest current streak of scoring 2+ goals in successive games on home soil in the competition (along with PSG).
Roma have failed to keep a clean sheet in 25 straight away Champions League games. Only Celtic (30 games in December 2016) have ever been on a longer such run in the competition.
Cengiz Under (20 years, 222 days) is Roma's second youngest Champions League goalscorer after Antonio Cassano in October 2002 against Genk (20 years, 82 days) and the youngest Turkish scorer in the competition, surpassing Hakan Calhanoglu (20 years, 235 days) when he scored for Bayer Leverkusen against Benfica in October 2014.
Edin Dzeko has been directly involved in five goals in the Champions League this season (three goals, two assists), his best return in a single campaign in the competition.
What's next?
Roma host AC Milan in Serie A on Sunday, 25 February (19:45 GMT), while Shakhtar host Zirka on the same day (15:00 GMT).
