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Before the latest round of Premier League fixtures, here is all the key injury news alongside essential Fantasy Premier League statistics.

The gameweek kicks off with West Ham United at home to Sunderland at Saturday lunchtime (12:30 GMT) - here is the full fixture list.

This article will be updated as Premier League managers give their weekly news conferences.

For more FPL help, don't miss our regular Friday Q&A from 15:30 BST live on the BBC Sport website, with one of our four experts answering your questions

Saturday

West Ham United v Sunderland (12:30 GMT)

West Ham United head coach Nuno Spirito Santo told Thursday's press conference that midfielder Lucas Paqueta will not feature amid transfer speculation linking the Brazil international with a move away during the January transfer window.

El Hadji Malick Diouf could be involved following the conclusion of the Africa Cup of Nations but Lukasz Fabianski remains out.

Sunderland duo Habib Diarra and Chemsdine Talbi have also returned from the continental tournament and "could" feature, according to head coach Regis Le Bris.

Arthur Masuaku, however, will be sidelined for up to six weeks after he sustained an ankle injury on international duty.

Players out: West Ham - Paqueta, Diouf, Fabianski Sunderland - Masuaku, Traore

Doubts: Sunderland - Diarra, Talbi

Key FPL notes:

  • West Ham's Crysencio Summerville (£5.5m) has scored in back-to-back matches in all competitions and was the highest FPL points scorer (10) against Spurs last time out. In Gameweek 22, only three midfielders attempted more shots (five).

  • Sunderland's Nordi Mukiele (£4.4m) is the seventh-highest scoring defender in FPL. Since Gameweek 16, only two defenders have produced more defensive contribution points (10).

  • Sunderland midfielder Enzo Le Fee (£4.9m) has produced one goal and an assist in the last three Gameweeks, averaging 4.0 points per start.

Burnley v Tottenham (15:00 GMT)

Burnley duo Joe Worrall and Zian Flemming are back in training following injury and could feature against Tottenham.

The Clarets are still missing five players, including Connor Roberts.

Tottenham may be missing up to eight players of their own for the trip to Turf Moor.

Midfielder Lucas Bergvall could miss up to three months after he was substituted in the midweek Champions League win against Borussia Dortmund with an ankle injury.

Joao Palhinha will be assessed, while Xavi Simons is expected to be available.

Players out: Burnley - Tresor, Cullen, Beyer, Roberts, Amdouni Tottenham - Bergvall, Maddison, Bentancur, Richarlison, Kudus, Kulusevski, Davies

Doubts: Burnley - Worrall, Flemming Tottenham - Palhinha

Key FPL notes:

  • Since Gameweek 18, only two goalkeepers have amassed more FPL points than the 22 of Burnley's Martin Dubravka (£4.0m).

  • Although he hasn't returned in FPL since Gameweek 11, Tottenham winger Wilson Odobert (£5.3m) has produced a goal and two assists in his last three matches in all competitions. In Gameweek 22, he had three shots and a team-high Expected Goal Involvement (xGI) of 0.47.

  • Only three defenders have delivered more FPL points than the 46 of Spurs' Cristian Romero (£5.0m) since Gameweek 14.

Fulham v Brighton (15:00 GMT)

Fulham duo Emile Smith Rowe and Kenny Tete are back in contention following injury, while Rodrigo Muniz has returned to training.

Sasa Lukic could be sidelined for up to five weeks after he was forced off in the 1-0 defeat at Leeds United last weekend.

Brighton continue to manage the fitness levels of several players, including Yankuba Minteh, although Maxim De Cuyper could feature following illness.

Mats Wieffer remains out with a toe injury.

Players out: Fulham - Lukic Brighton - Wieffer, Tzimas, Webster, March

Doubts: Fulham - Smith Rowe, Tete, Muniz

Key FPL notes:

  • Since Gameweek 13, no player in the game has amassed more FPL points than the 68 of Fulham winger Harry Wilson (£5.9m).

  • Joachim Andersen (£4.6m) is Fulham's second-highest-scoring player with 78 points. He has returned defensive contribution points in four of the last seven Gameweeks.

  • Jan Paul van Hecke (£4.5m) is Brighton's leading points scorer with 84 points. He produced his fifth attacking return of the season against Bournemouth in Gameweek 22.

Manchester City v Wolves (15:00 GMT)

Manchester City manager Pep Guardiola told Friday's press conference that new signing Marc Guehi will make his debut on Saturday.

City have selection issues in central defence, with John Stones, Ruben Dias and Josko Gvardiol all sidelined, meaning Guehi will step in straight away.

Matheus Nunes will be assessed following illness although Nico Gonzalez is set to remain out.

Wolves striker Jorgen Strand Larsen is in contention to feature at the Etihad despite being subject to a failed bid by Leeds United earlier this week.

"He's been great, trained really well and will be part of the squad tomorrow," said head coach Rob Edwards on Friday.

Players out: Manchester City - Savio, Gonzalez, Bobb, Dias, Stones, Kovacic, Gvardiol Wolves - Toti, Bellgarde

Doubts: Manchester City - Nunes Wolves - Chirewa

  • Phil Foden's (£8.6m) 44 shots and 38 chances created are both among Manchester City's top three players this season.

  • Marc Guehi (£5.2m) is the most-owned defender in Fantasy, with his ownership currently sitting at 37.7% following his move from Crystal Palace to City.

  • Since Gameweek 19, only three defenders have accumulated more FPL points than Hugo Bueno (£4.3m). The Wolves defender has delivered two assists, two clean sheets and two bonus points across that timeframe.

Bournemouth v Liverpool (17:30 GMT)

Bournemouth's injury crisis continues, with head coach Andoni Iraola confirming on Friday that Marcus Tavernier will be out for "some time" because of the hamstring injury sustained in the 1-1 draw at Brighton on Monday.

New signing Alex Toth could make his debut, while Enes Unal has returned to training.

Liverpool forward Mohamed Salah will be "ready to play", according to Arne Slot, although the Reds manager told Friday's press conference that he is yet to decide whether the 33-year-old will start.

"Mo played 90 minutes and yesterday we had a recovery session, we trained today and knowing Mo he is ready to play tomorrow," said Slot.

"But he, like all the others, have a training session to go and then I will decide on the line-up."

Ibrahima Konate, who missed the midweek Champions League win against Marseille, remains unavailable after his father passed away.

Players out: Bournemouth - Kluivert, Brooks, Soler, Adams, Doak, Dennis Liverpool - Bradley, Leoni, Isak, Konate

Doubts: Bournemouth - Unal Liverpool - Chiesa

Key FPL notes:

  • Bournemouth teenager Junior Kroupi (£4.6m) has scored seven goals this season, two of which have come in the last three Gameweeks.

  • Since Gameweek 16, no midfielder has picked up as many FPL points as the 49 of Liverpool's Florian Wirtz (£8.3m). In that time, he has returned three goals, an assist and 12 bonus points.

  • Liverpool striker Hugo Ekitike (£8.9m) has produced five goals and an assist in his last six matches, amassing 44 points.

Sunday

Brentford v Nottingham Forest (14:00 GMT)

Brentford have no new injury concerns as they prepare to host Nottingham Forest.

Midfielder Jordan Henderson could return after missing the defeat at Chelsea last weekend because of an ankle injury.

Frank Onyeka is available following the Africa Cup of Nations.

Nottingham Forest duo Igor Jesus and Murillo will be assessed after missing Thursday's Europa League defeat to Braga.

Chris Wood and John Victor remain out.

Players out: Brentford - Carvalho, Milambo, Dasilva Nottingham Forest - Victor, Wood

Doubts: Brentford - Henderson Nottingham Forest - Jesus, Murillo

Key FPL notes:

  • Since Gameweek 17, no outfield player has amassed more points than the 45 of Brentford's Nathan Collins (£5.0m).

  • Nottingham Forest's Elliot Anderson (£5.3m) has returned defensive contribution points 15 times this season - no midfielder has produced more.

  • Forest forward Igor Thiago (£7.2m) has five goals and an assist in his last five matches. This season, only Erling Haaland (£15.1m) has scored more goals than the Brazilian's 16.

Crystal Palace v Chelsea (14:00 GMT)

Crystal Palace striker Jean-Philippe Mateta will play against Chelsea, according to manager Oliver Glasner, after the France international reportedly indicated earlier this week that he wanted to leave the club in January.

Ismaila Sarr is in contention to feature after returning from international duty, while Nathaniel Clyne is also set to be included following injury.

Chelsea head coach Liam Rosenior told Friday's press conference that midfielder Cole Palmer is in a "good place" and will be assessed following training.

Filip Jorgensen could return in time to face Napoli in the Champions League on Wednesday but Dario Essugo will be sidelined for around a month.

Players out: Crystal Palace - Kamada, Doucoure, Cardines, Munoz, Nketiah, Kporha Chelsea - Adarabioyo, Colwill, Lavia, Jorgensen, Essugo

Doubts: Chelsea - Palmer, Fernandez

Key FPL notes:

  • Crystal Palace defender Maxence Lacroix (£5.1m) has racked up 236 defensive contributions this season. Twenty four defensive contribution points have come about because of this.

  • Over the last four Gameweeks, Chelsea's Enzo Fernandez (£6.5m) has produced 27 points, the third-most of any FPL midfielder.

  • Four of Blues forward Pedro Neto's (£7.1m) five goals this season have arrived away from home, where he is averaging 4.0 points per start.

Newcastle United v Aston Villa (14:00 GMT)

Newcastle United will assess the fitness of midfielder Bruno Guimaraes, who was forced off during Wednesday's Champions League win against PSV Eindhoven because of an ankle injury.

"Bruno we hope it is not serious," head coach Eddie Howe told Friday's press conference. "It is still unknown. We will give him every chance this weekend."

Defender Dan Burn, who has not featured since 14 December, has returned to training.

Aston Villa forward Leon Bailey could make his first Premier League appearance since May after returning from a loan spell at Roma.

Boubacar Kamara, Ross Barkley and John McGinn remain out.

Players out: Newcastle - Schar, Murphy, Krafth, Livramento Aston Villa - Kamara, Barkley, McGinn,

Doubts: Newcastle - Burn, Guimaraes, Osula Aston Villa - Martinez

Key FPL notes:

  • Newcastle defender Lewis Hall (£5.3m) has produced a return in each of his last four matches, with an assist, two clean sheets, three bonus and two defensive contribution points.

  • Magpies goalkeeper Nick Pope's (£5.1m) highest FPL score of 2025-26 so far came in the reverse fixture, where he produced nine points thanks to a clean sheet, three saves and two bonus.

  • Despite blanking, Aston Villa midfielder Morgan Rogers (£7.7m) racked up six shots in Gameweek 22, the joint-most of any player.

Arsenal v Manchester United (16:30 GMT)

Arsenal have no new injury concerns ahead of their meeting with Manchester United.

Piero Hincapie and Riccardo Calafiori have both returned to training but Max Dowman remains out.

Manchester United welcome back Shea Lacey from suspension, while Noussair Mazraoui is now available after his involvement in the Africa Cup of Nations.

Matthijs de Ligt and Joshua Zirkzee are still sidelined.

Players out: Arsenal - Dowman, Havertz Manchester United - De Ligt, Zirkzee

Key FPL notes:

  • No FPL defender has scored on more occasions than Arsenal's Gabriel (£6.9m) in 2025-26 (three).

  • No player has created more chances than Bruno Fernandes (£9.2m) this season (62), having supplied nine assists in 19 matches. The Manchester United captain is the most-bought player ahead of Gameweek 23, earning over 404,000 new owners.

  • Deployed in a central strike role, United forward Bryan Mbeumo (£8.1m) finished Gameweek 22 joint-top for big chances, with two.

Monday

Everton v Leeds United (20:00 GMT)

Everton manager David Moyes says that the club are still waiting to establish the timeline of Jack Grealish's absence after it was revealed earlier this week that the England international had sustained a stress fracture to his foot.

Idrissa Gueye and Iliman Ndiaye have returned from winning the Africa Cup of Nations with Senegal and could be involved.

Carlos Alcaraz, Kiernan Dewsbury-Hall and Jarrad Branthwaite are all back in training.

Leeds United boss Daniel Farke told Thursday's press conference that Gabriel Gudmundsson has been unable to train because of an abductor injury and is at risk of missing a first Premier League game of the season.

Anton Stach has returned to training and will be assessed but Dan James remains out.

Players out: Everton - Grealish, Keane, Iroegbunam Leeds - James

Doubts: Everton - Dewsbury-Hall, Branthwaite, Alcaraz Leeds - Bijol, Stach, Gudmundsson

Key FPL notes:

  • Defender James Tarkowski (£5.7m) is Everton's top-scoring player in 2025-26, delivering 108 points thanks to one assist, nine clean sheets, 32 defensive contribution points and six bonus.

  • Toffees midfielder James Garner (£5.2m) produced defensive contribution points for the seventh consecutive match in Gameweek 22, the longest streak of any player this season.

  • Leeds striker Dominic Calvert-Lewin (£6.0m) has returned 65 points over his last 10 appearances, combining eight goals with one assist and 13 bonus.

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