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Drama series about Jackie Peyton, a no-nonsense emergency room nurse based in New York, who has to balance her frenzied job with a complicated home life.

Jackie cuts through red tape to speed up a boy's diagnosis, irritating Dr. Cooper, who has taken to Twitter as a way to vent his anger. Mourning her mother's death, O'Hara shows up after a night of clubbing so Jackie covers for her while she comes down from ecstasy. Eddie visits the bar and continues his friendship with Kevin.