Programme Information

Syed asks Tamwar why he told Amira about his past, in today's visit to the Square. Tamwar says he is unhappy that Syed is always the golden boy.

Meanwhile, Denise is uneasy about meeting Owen. Lucas tries to calm her down but she recalls the horrid memories of what he did to Libby.

Syed is played by Marc Elliott, Tamwar by Himesh Patel, Amira by Preeya Kalidas, Denise by Diane Parish, Owen by Lee Ross, Lucas by Don Gilet and Libby by Belinda Owusu.

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When Donna has to deal with Derek's meagre effects, she finds herself setting off on a trip that begins as a joy-ride and ends with her having to confront some serious responsibilities, as the medical drama continues. Along the way, she learns a lot more about her father – and discovers a new family member.

Joseph's determination to get to the bottom of Faye's suspension drives him to compromise his professionalism by confronting Lauren, against Michael's advice.

Judith is determined to prove her sceptics wrong but, when her new infection-control measures backfire and Mark saves the day, Judith realises Mark is worth his weight in gold.

Donna is played by Jaye Jacobs, Joseph by Luke Roberts, Faye by Patsy Kensit-Healy, Michael by Hari Dhillon, Judith by Shelagh McLeod, Maria by Phoebe Thomas and Mark by Robert Powell.

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Around The World In 80 Days Ep 3/6

Tuesday 27 October

9.00-10.00pm BBC ONE

• Feature
• Press pack

Julia Bradbury and Matt Baker on their leg of the Around The World In 80 Days challenge

Countryfile presenters Julia Bradbury and Matt Baker pick up the baton for the third leg of the Around The World In 80 Days challenge. In 13 days' time, they have to be in China to hand over to BBC Breakfast presenter Bill Turnbull and BBC News presenter Louise Minchin. From Almaty in Kazakhstan, they race to catch the first of five trains which will carry them on their way.

After a good start, and their first night on a train, Matt and Julia wake up close to Semey in Kazakhstan, a city with an intriguing past as a nuclear-testing site. Here, they meet an interesting nuclear scientist and go to see the radioactive exhibits at the museum.

On day three, as they prepare to leave Kazakhstan for Russia, Julia and Matt find a glitch in their plan when the customs police don't allow them to enter. Without being able to leave the tiny Russian border town of Rubtsovsk and, with no filming allowed, time and the challenge seem to be slipping away. Hours later, they get the all clear and hurriedly get on their way. Can they make up the lost time and make sure the challenge is not left in tatters?

The rest of the journey is a race against the clock in a bid to get the challenge back on track. Driving through the night, they journey on the Trans-Siberian railway and then on to another train which should take them to Mongolia. But, with another border crossing ahead, will the team negotiate the red tape to keep the relay on track?

Around The World In 80 Days is simulcast on the BBC HD channel – the BBC's High Definition channel, available through Freesat, Sky and Virgin Media.

GD/JF/LK

James May with his full-size Spitfire made of Airfix

James May sets out to prove that traditional toys are still relevant today when he pushes them to the limit in spectacular, supersize challenges. From a full-size Lego house to a bridge made completely of Meccano, he shows just what extremes toys can be pushed to.

In the first of six programmes, James takes model airplanes to a whole new level when he tries to build and paint a life-size Spitfire out of Airfix, over the course of 3 days at the RAF Museum Cosford. But the venture soon hits problems when it becomes clear that the giant 36-foot pieces may not be strong enough, and nobody knows how they will fit together.

James hopes he can enthuse a group of reluctant teenagers to help him pull it off – but he soon realises he has another big battle on his hands convincing them that this is a hobby to be proud of.

TD

Horizon follows the emotional journey of three young people with currently untreatable conditions to see if, within their lifetime, they can be cured.

Sophie Morgan is determined not to spend the rest of her life in a wheelchair. She is tempted by the online claims of unregulated private clinics promising a cure using stem cells. To help her decide if she should go for treatment, she meets another paraplegic, Chris Oberle, who spent his life savings visiting an Indian clinic. She also visits Geron, the Californian clinic set to hold the first human trials using embryonic stem cells. A lot rests on the trial; if successful, it could mean treatment much sooner for Sophie and lead to cures for a range of untreatable conditions.

Anthony Bath was just 20 when his right leg was amputated. A botched pinning procedure led to an MRSA infection and, after 18 operations, the loss of his leg. Although he has continued to achieve great things on the sporting front, running marathons and sailing around the world, he would still love to have his leg back. In Finland, Anthony witnesses one of the world's first operations in which stem cells are used to replace bone. If the procedure had been available a few years ago, his leg could have been saved.

When Dean Third collapsed, he was diagnosed with dilated cardiomyopathy, a condition in which his damaged heart could cause his death at any moment. His condition is stabilised by medication, but each of his children carries a 50 per cent chance of developing symptoms, too. Desperate for a cure, he visits Dr Anthony Mathur from University College London in his operating theatre to witness the world's first trial using stem cells taken from bone marrow. They are then injected directly into the muscles of the heart with the aim of regenerating the damaged heart cells.

For Sophie, Anthony and Dean, this pioneering research could mean the difference between the life they are forced to lead and the life they dream of. Throughout the film, they reflect on what these discoveries could mean for them, and whether they really believe that, in the future, stem cells could heal them.

VAA