Blood
The composition of blood
Blood transports materials and distributes heat around the body. It also helps to protect against disease. Blood contains plasmaLiquid, non-cellular part of the blood., which is a liquid that the other components of blood are suspended in.
Plasma is a straw-coloured liquid that makes up just over half the volume of blood.
This table explains the functions of various blood components.
| Component | Function(s) |
| Plasma | Transporting dissolved carbon dioxide, digested food molecules, urea and hormones; distributing heat |
| Red blood cells | Transporting oxygen |
| White blood cells | Ingesting pathogens and producing antibodies |
| Platelets | Involved in blood clotting |
| Component | Plasma |
|---|---|
| Function(s) | Transporting dissolved carbon dioxide, digested food molecules, urea and hormones; distributing heat |
| Component | Red blood cells |
|---|---|
| Function(s) | Transporting oxygen |
| Component | White blood cells |
|---|---|
| Function(s) | Ingesting pathogens and producing antibodies |
| Component | Platelets |
|---|---|
| Function(s) | Involved in blood clotting |
Red blood cells
Red blood cells (also called erythrocytesAnother word for red blood cells) transport the oxygen required for aerobic respirationRespiration that requires oxygen. in body cells.
They must be able to absorb oxygenGaseous element making up about 20% of the air, which is needed by living organisms for respiration. in the lungs, pass through narrow blood capillaryTiny blood vessels with walls one-cell thick where exchange of materials occurs., and release this oxygen to respireTo engage in respiration, the energy-producing process inside living cells. cells.
Red blood cells have several adaptations that enable them to carry out this function:
- They contain the proteinOrganic compound made up of amino acid molecules. One of the three main food groups, proteins are needed by the body for cell growth and repair.haemoglobinThe red protein found in red blood cells that transports oxygen round the body., which gives them their red colour
- \(\text{haemoglobin} + \text{oxygen} \rightleftharpoons \text{oxyhaemoglobin}\)
- Haemoglobin can combine reversibly with oxygen. This is important - it means that it can combine with oxygen as blood passes through the lungs, and release the oxygen when it reaches the cells.
- They have no nucleusThe nucleus controls what happens inside the cell. Chromosomes are structures found in the nucleus of most cells. The plural of nucleus is nuclei. so they can contain more haemoglobin.
- They are small and flexible so that they can fit through narrow blood capillaries.
- They have a biconcave shape - they are the shape of a disc that is curved inwards on both sides - to maximise their surface area for oxygen absorption.
- They are thin, so there is only a short distance for the oxygen to diffuse to reach the centre of the cell.

White blood cells
There are several types of white blood cell.
Phagocytes
About 70 per cent of white blood cells are phagocytesCells, such as white blood cells, that engulf and absorb waste material, harmful microorganisms, or other foreign bodies in the bloodstream and tissues.. Phagocytes engulf and destroy unwanted microorganisms that enter the blood, by the process of phagocytosisThe process of the ingestion of bacteria or other material by phagocytes..
Lymphocytes
Lymphocytes make up about 25 per cent of white blood cells. Lymphocytes produce soluble proteins called antibodyA protein produced by the immune system in humans (and other animals) that attacks foreign organisms (antigens) that get into the body. when a foreign body such as a microorganism enters the body.
Antibodies neutralise pathogens in a number of ways:
- they bind to pathogens and damage or destroy them
- they coat pathogens, clumping them together so that they are easily ingested by phagocytes
- they bind to the pathogens and release chemical signals to attract more phagocytes
Lymphocytes may also release antitoxins that stick to the toxins that the microorganism makes, which stops it damaging the body.
Both phagocytes and lymphocytes are part of the body's immune systemThe body's defence system against entry of any foreign body, including pathogens and agents such as pollen grains. The role of the immune system is to prevent disease..

Platelets
Platelets are cell fragments produced by giant cells in the bone marrowSoft tissue found inside bones that produces new blood cells..
Platelets stop bleeding in two main ways:
- they have proteinOrganic compound made up of amino acid molecules. One of the three main food groups, proteins are needed by the body for cell growth and repair. on their surface that enable them to stick to breaks in a blood vessel and clump together
- they secrete proteins that result in a series of chemical reactions that make blood clot, which plugs a wound
Image caption, Platelets help blood to clot
Image caption, Platelets help blood to clot
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