Attempts to treat and cure illness and disease - EduqasJoseph Lister and the use of antiseptics

The treatment of illness and disease has changed due to improvements in medical knowledge. Treatments have become increasingly successful. How have attempts to treat illness and disease changed over time?

Part ofHistoryChanges in health and medicine in Britain, c.500 to the present day

Joseph Lister and the use of antiseptics

Until the acceptance of germ theory in the 1860s, surgeons did not take any precautions to protect open wounds from infection. They did not wash their hands before operating, sterilise their equipment or clean the operating table.

Early surgery, circa 1870 - a cloth covered in chloroform is being held over a patient's face and carbolic spray worked by a steam apparatus is creating an antiseptic atmosphere.
Figure caption,
Early anaesthetic surgery, c.1870. The assistant on the left is holding a chloroform-covered cloth over the patient’s face. Carbolic spray can be seen on the stool, creating an antiseptic atmosphere

This began to change in 1867, when Joseph Lister discovered that carbolic spray was very effective in stopping wounds from developing He developed surgery by spraying medical instruments, and bandages with a 1-in-20 solution of carbolic acid.

As always, there was some opposition.

  • Many surgeons claimed that Lister’s antiseptic methods slowed things down at a time when speed was still essential because of blood loss.
  • Lister could be very critical of other surgeons. Therefore, some were reluctant to accept his ideas.
  • Many surgeons lived with the fact that lots of patients would die - for them it was an acceptable part of surgery.

Despite this opposition, it was soon obvious that Lister’s methods were a success. In just three years, he reduced the death rate among his patients from 46 to 15 per cent. Others soon copied his methods. In the 1880s were being carried out, and in 1896 surgeons performed the first major cardiac surgery when they repaired a heart damaged by a stab wound.

Reducing the death rate

In the latter part of the 19th century, there were other developments that further reduced the death rate from surgery:

  • In the 1860s, standards of hospital cleanliness and nursing care rose rapidly once Florence Nightingale returned to the UK. She had been nursing in the Crimean War. She enforced high standards of cleanliness to reduce infection among wounded soldiers.
  • The 1890s saw the beginnings of Surgical instruments were steam- sterilised. Surgeons started using sterilised gowns, rubber gloves and face masks to further reduce the risk of infection.
  • In the early 20th century, X-rays allowed surgeons a look inside the body before operating.

Blood loss

The one remaining problem, blood loss, was overcome in the early 20th century. In 1901 an Austrian, Karl Landsteiner, discovered blood groups. had been tried before but usually killed the patient because giving them a different blood group resulted in blood clotting inside the body.

Matching blood groups stopped this from happening. World War One acted as a catalyst for the rapid development of blood banks and transfusion techniques. In 1938 the National Blood Transfusion Service was set up in Britain.