Reproduction, the genome and gene expression - AQA Protein synthesis - Higher

Reproduction occurs in all organisms. DNA is important, as it allows new proteins to be synthesised. Mutations in the DNA can have serious implications.

Part ofBiology (Single Science)Inheritance, variation and evolution

Protein synthesis - Higher

Greg Foot explains how the structure of DNA affects the proteins made in DNA synthesis.

consists of two stages – transcription and translation. In transcription the DNA code is read, and in translation the code is used to build up molecules.

DNA is a triplet code. Each triplet, a group of three bases, codes for a specific amino acid.

Diagram showing how protein is synthesised in a DNA structure
Figure caption,
An overview of the process of protein synthesis.

Transcription and translation

DNA is often called the genetic code. It is the code to make proteins. DNA remains in the , but during transcription a copy is made from mRNA. This moves from the nucleus to a in the .

Diagram illustrating the process of transcription - when a gene is converted to protein
Figure caption,
A detailed view of the process of transcription - making an mRNA copy of a gene's worth of DNA in the nucleus.

During translation, proteins are synthesised in ribosomes. During this process, carrier molecules, called tRNA, bring specific amino acides to add in the correct order to the growing protein. There are only about 20 different naturally-occuring amino acids.

Each protein molecule has hundreds, or even thousands, of amino acids joined together in a unique sequence. It is then folded into the correct unique shape. This is very important, as it allows the protein to do its job. Enzymes and hormones are proteins and their correct shapes are crucial to their functions.

The protein produced depends on the DNA code used, and if this sequence changes a different protein could be made.

Image gallerySkip image gallerySlide1 of 2, Amino acid sequence 1 showing acid chain folding into precise shape, Different amino acid sequences result in proteins folding into different shapes, with protein one functioning as an enzyme.
A model of haemoglobin
Image caption,
A molecular model of haemoglobin, a protein found in red blood cells

Learn more about protein synthesis with Dr Alex Lathbridge.

Learn about how proteins are made during the processes of transcription and translation.