Organisms are made up of cells. Most organisms are multicellular and have cells that are specialised to do a particular job. Microscopes are needed to study cells in detail.
No-one knows who first invented the microscope, but there have been key stages in their development:
1590s - Dutch spectacle makers Janssen experimented with putting lenses in tubes. They made the first compound microscopeA compound microscope uses two lenses, the objective lens and the eyepiece. The very short focal length objective lens produces a greatly-magnified image, then the short focal length eyepiece magnifies this further. .
None of their microscopes have survived, but they are thought to have magnified from ×3 to ×9.
1650 - British scientist, Robert Hooke 1650 – also famous for his law of elasticity in Physics – observed and drew cells using a compound microscope.
Antonie van Leeuwenhoek's first microscope, (17th century)
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Slide1 of 2, A replica of Robert Hooke's compound microscope, A replica of Robert Hooke's compound microscope
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Late 1600s – Dutch scientist Antonie van Leeuwenhoek constructed a microscope with a single spherical lens. It magnified up to ×275.
1800s - the optical quality of lenses increased and the microscopes are similar to the ones we use today.
Throughout their development, the magnification of light microscopes has increased, but very high magnifications are not possible. The maximum magnification with a light microscope is around ×1500.