A joint study between Bangor University and Aberdeen University is studying E.coli infections in rural areas. Dr Prysor Williams of the School of Enviroment, Natural Resources & Geography in Bangor joins Adam Walton to discuss E.coli bacteria, particularly E.coli O157, which can cause serious health problems.

By 2018 the European Extremely Large Telescope is due to be up and running, offering astronomers across Europe incredible views of the Southern skies (it will be based in Chile because of the favourable properties of the night sky there). OpTIC Glyndwr in St Asaph are hoping to produce the precision mirror panels for the telescope, and this month will begin their trials using innovative new technology. Science Cafe reporter Tracy Cardwell visits St Asaph and discusses the details with Professor David Walker.

A collaboration between Cardiff University and Rothamstead Research in Hertfordshire hopes to use some "blue sky thinking" to come up with new environmentally-friendly forms of pest control using nature's own enzymes. Professor Rudolf Allemann from the School of Chemistry in Cardiff and Professor John Pickett from Rothamstead join the programme to explain the science behind the research and how it could lead to future improvements in anti-cancer and anit-malaria drugs.

With the National Eisteddfod taking place in Ebbw Vale this week, the Science Cafe reflects on some of the scientists and innovators who worked in Blaenau Gwent and the surrounding area over the centuries. Author and historian John Evans discusses the achievements of Samuel Baldwin Rogers, the Allgood family, and Sidney Gilchrist Thomas