Russia's Mikhail Youznhy, the 12th seed at Flushing Meadows, takes an early advantage in his fourth-round tie against Spain's Tommy Robredo
Robredo, who is ranked 41 in the world but has been as high as number five, is one of five Spaniards still in action at Flushing Meadows on day nine of the tournament
The Russian wins the first two sets as he aims to repeat his 2006 performance, when he reached the semi-finals, but Robredo takes the third set
But it is Youzhny who is celebrating after wrapping up a 7-5 6-2 4-6 6-4 win over Robredo in three hours and five minutes
There is still something for British fans to cheer at the US Open as Laura Robson beats Chanelle van Nguyen in straight sets to reach the last 16 in the girls' singles
Britain's George Morgan is another casualty in the boys' singles, losing out in straight sets to Filip Horansky of Slovakia
Home hopes in the men's singles rest with the 20th seed Sam Querrey, who takes on Andy Murray's conqueror Stanislas Wawrinka
Swiss player Wawrinka, who defeated Andy Murray in four sets on Sunday, shows no ill-effects from the thigh injury that troubled him against the Scot as he reaches for a shot against Querrey
After going two sets to one down to Wawrinka, Querrey recovers his composure to win the fourth set and send the match to a decider
But after four and a half hours it is Wawrinka who is the one celebrating a place in the last eight after a 7-6 6-7 7-5 4-6 6-3 success
Two-time winner and third seed Venus Williams returns the ball to Francesca Schiavone, the sixth seed, in their quarter-final tie with Williams hoping to continue her unbeaten record against the Italian
Schiavone battles hard in the first set but two forehand errors at the end of the tie-break see her slip behind
Williams twice lets a lead slip in the second set but breaks Schiavone for a third time to seal a 7-6 (7-5) 6-4 victory and a place in the last four
Defending champion Kim Clijsters comes into her quarter-final with Sam Stosur on an 18-match winning streak at Flushing Meadows
Stosur has her chances as she breaks serve three times in the final set but it is Clijsters who holds her nerve for a 6-4 5-7 6-3 win
Over on Louis Armstrong Stadium, David Ferrer takes charge with a two-set lead over fellow Spaniard Fernando Verdasco
Verdasco refuses to yield, however, fighting back from two sets down, a break down in the fifth set and then 4-1 down in the final set tie-break
Verdasco celebrates a remarkable 5-7 6-7 6-3 6-3 7-6 win and a place in the quarter-finals
Rafael Nadal is the star attraction in the day's final match as he takes on fellow Spaniard and good friend Feliciano Lopez
Lopez is not the first player to find it hard going against the world number one and he soon finds himself two sets down
Nadal completes a 6-3 6-4 6-4 victory to end a dramatic day nine and secure himself a quarter-final against Verdasco
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