 Hantuchova dropped out of the world top 50 in 2004 |
Daniela Hantuchova moved into the quarter-finals in Dubai, after beating Elene Likhotseva of Russia 7-5 6-4, and now faces Serena Williams. Australian Open champion Williams survived an early scare to beat Russia's Elena Bovina 1-6 6-1 6-4.
World number one Lindsay Davenport and Anastasia Myskina also progressed.
Davenport defeated China's Jie Zheng 6-2 7-5, while French Open champion Myskina sailed through after her opponent Marion Bartoli retired hurt.
American Davenport will now face fellow former Wimbledon champion, Conchita Martinez of Spain, who ousted seventh-seeded Nathalie Dechy of France 6-1 6-2.
Myskina will face eighth-seed Patty Schnyder from Switzerland, who defeated China's Li Na 6-3 7-6 (10-8).
The other quarter final pits wild card Sania Mirza of India against Jelena Jankovic of Serbia and Montenegro, who both won on Tuesday.
 | It was really windy and I hadn't played in the wind. All my shots were going out of here |
Before her meeting with Martinez, Davenport believes there is some room for improvement in her game.
"I started well and finished well, but played some so-so games in the middle," she said.
Williams was also far from content.
"I don't know what I was doing there," she said. "It was really windy and I hadn't played in the wind. All my shots were going out of here."
But Hantuchova is in upbeat mood ahead of her clash with the younger Williams sister, who was handed a first-round bye.
"I feel I have an advantage (over Serena) because I have already played two matches on these courts," she said.
"It is a difficult court to play on. Very fast and sometimes you feel you have no control over the ball."