Allan Jacobsen has won 22 caps for Scotland

The Edinburgh forward will be replaced by Gloucester prop Alasdair Dickinson, who turns 24 on Tuesday and has yet to win a Scotland cap.

Scotland coach Frank Hadden paid tribute to Jacobsen.

"It's a disappointment to lose him. He worked incredibly hard over the summer and was in great shape," he said.

Hadden said he had no doubt Dickinson was ready to make the step up, despite his inexperience.

"Ally was also part of our preparation squad so is very much up to speed with what we do, and he has worked assiduously on his development as a player," Hadden told Scotland's website.