Titterrell last played for England in 2005

The 26-year-old hooker, who has four England caps and was a Lions tourist in 2005, has signed a three-year deal.

Titterrell said: "It's a fantastic club, one of the strongest and most progressive in Europe, and I'm thrilled to be joining them."

"Andy's an international-quality footballer. The chance to sign those sorts of players does not come around often," said Gloucester boss Dean Ryan.

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"He is an individual who impresses us greatly, he has tremendous determination to be successful and that is the sort of attitude we want at this club."

Titterrell made his Sale debut in 2001 and has now made 121 Premiership appearances and scored seven tries.