Wales' women failed to match their male counterparts as they crashed to a third heavy defeat Six Nations defeat. Playing immediately after the men's match at Murrayfield, Scotland led 8-0 at the interval thanks to a penalty and slick Lucy Millard try.
Millard added another touchdown after the break, with Suzi Newton crossing in the closing stages as Scotland posted their third successive victory.
Wales' final chance of claiming a win comes at home to Ireland on Friday.
Wales Women: Elen Evans (Dolgellau); Non Evans (Clifton), Rhian Williams (Wasps), Lowri Jones (Bala), Louise Rickard (Saracens); Awen Thomas (Cardiff Quins), Kerry Jenkins (UWIC); Louise Horgan (Saracens), Jennifer Davies (Caernarfon), Claire Horgan (Waterloo), Ayla Rose (Llandaff North), Claire Donovan (Saracens), Catrina Nicholas (UWIC), Kylie Wilson (Waterloo), Emma Phillips (Llandaff North).
Replacements: Sophie Williams (Richmond), Ruth Copeland (Llandaff North), Rebecca Dando (Cardiff Quins), Rachel Brown (Waterloo), Becky Davies (Cardiff Quins), Stacey Saunders (Tylorstown), Hayley Baxter (UWIC).