The contest was as one-sided as the scoreline suggests and Bristol were never in contention after Aguero forced his way over following a pass from Jackson.
Flanker Andy Saull then exploited a gap in the Bristol defence to race clear before off-loading to Barritt who strolled over.
The visitors responded with Linklater scoring in the corner but the hooker suffered a leg injury soon after and had to be replaced.
It was cruel luck on Bristol, who already had an entire front row out injured, and they fell further behind when Jackson kicked three penalties in the final 10 minutes of the half.
Skirving marked his return to the starting line-up, in place of injured Wales international Michael Owen, by diving in low after the break to extend Sarries lead.
Bristol's David Blaney was sin-binned late on for killing the ball and Saracens cashed in, driving Borthwick over from a line-out to score the bonus-point try.
Saracens boss Eddie Jones on fly-half Glen Jackson:
"His goal-kicking was good and his out-of-hand kicking is just wonderful. England should really consider having him in the squad.
"If they are going to have (Danny) Cipriani and (Toby) Flood as their major stand-offs maybe they should have someone like Jackson, who understands the game exceedingly well, in the squad to teach these younger guys how to play because I think they need a mentor."
Bristol head coach Richard Hill reflects on nearest rivals Newcastle's shock victory at Gloucester:
"It was a very good win for Newcastle and we've got to stew on that for four weeks and get our act together. We have to beat Newcastle.
"There was pressure on us to win that one anyway but now we just have to win."
On the Bristol game, Hill added: "I don't think it could have been worse. Endeavour and heart was there but the quality was lacking again.
"Some of the passing was not good and we coughed up possession too easily. Our kicking was unbelievably poor and individuals are not playing well."
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