Stoner was never challenged for the lead in the race

John Hopkins came a career-best second after a superb start from fourth on the grid, with defending champion Nicky Hayden third and Dani Pedrosa fourth.

Valentino Rossi, who lies second behind Stoner in the standings, had a miserable day as he finished seventh.

Stoner's championship lead over Rossi is now 60 points, with Pedrosa just 18 points behind Rossi in third place.

The victory at the undulating 5.4-km Masaryk Ring was Stoner's seventh in 12 races this season.

"Everything worked perfectly today, the bike, the tyres. I was fast at the beginning... so I could relax slightly towards the end," said the 21-year-old.

American John Hopkins, who started from the front row, led his Suzuki unchallenged to claim second place.

"Casey's pace was unreal, he didn't make a mistake the whole race so it was tough to catch him," said Hopkins.

Czech MotoGP race result:

1 Casey Stoner (Aus) Ducati 43min 45.810secs
2 John Hopkins (US) Suzuki 43:53.713
3 Nicky Hayden (US) Honda 43:58.910
4 Dani Pedrosa (Spn) Honda 44:01.610
5 Chris Vermuelen (Aus) Suzuki 44:03.113
6 Loris Capirossi (It) Ducati 44:05.173
7 Valentino Rossi (It) Yamaha 44:08.295
8 Randy de Puniet (Fr) Kawasaki 44:08.883
9 Alex Barros (Brz) D'Antin Ducati 44:18.102
10 Carlos Checa (Sp) Honda 44:20.963

Overall standings:
1 Stoner 246 points
2 Rossi 186
3 Pedrosa 168
4 Vermeulen 124
5 Hopkins 124