Rooney also missed England's 2-0 friendly defeat against European champions Spain in which Aston Villa pair Emile Heskey and Gabriel Agbonlahor started up front.
United have put together seven consecutive wins in all competitions without the forward, progressing in both cups and moving two points clear of second-placed Liverpool in the Premier League, with Wednesday's game at Old Trafford in hand.
Ferguson added: "We have handled him in the right way. His performances in training have been excellent."
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