Luton Town's hopes of another trip to Wembley were dashed as poor defending cost them dearly in the FA Trophy first round at Cambridge United.
Danny Crow was unmarked to put the U's ahead after six minutes, while strike partner Chris Holroyd added two more before the break.
He was unmarked to head in the second on the half hour then netted from Wayne Hatswell's miss-hit long-range shot.
A Hatswell own goal gave JP Trophy holders Luton a late consolation.
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Luton manager Richard Money told BBC Three Counties Radio:
"I thought we started brightly enough and to be honest, in the first half there was nothing in the game except that we couldn't defend three crosses.
"I'm pleased that we have won the second half."
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