Manchester United 3-1 Tottenham Hotspur: The opening goal arrives shortly before the hour when Ryan Giggs converts a penalty for Manchester United after a foul by Benoit Assou-Ekotto on Patrice Evra
With Aaron Lennon on for his first game in several months, Spurs push for an equaliser and get it when Ledley King heads home from Gareth Bale's corner in the 70th minute
To Harry Redknapp's disappointment, parity only lasts for 11 minutes as substitute Federico Macheda puts in Nani who chips the title chasers back into the lead
Sir Alex Ferguson's side make sure of their return to the top of the table when Nani wins another penalty which Giggs again converts to wrap-up victory
Arsenal 0-0 Manchester City: Former Gunners stars Patrick Vieira and Emmanuel Adebayor return to their former club but while the former is well received, the other gets booed as he replaces him
In a game of few chances, one of the main talking points is the painful shoulder injury suffered by City's goalkeeper Shay Given who leaves the action on a stretcher
West Ham United 3-2 Wigan Athletic: The Hammers make a dreadful start when Jonathan Spector scores an own goal but they respond well and equalise just after the half hour when Ilan finishes from Carlton Cole's cross
Gianfranco Zola's team give their supporters more to celebrate when Radoslav Kovac heads a second, just seconds before half-time, after goalkeeper Chris Kirkland fails to hold Mark Noble's free-kick
Sadly for them the lead evaporates seven minutes into the second half when Hugo Rodallega gets the final touch after Ben Watson's corner causes problems in the box
With the Latics starting to get the better of things and the atmosphere at Upton Park starting to go flat, Scott Parker unleashes an unstoppable 25-yard drive to win it for West Ham
Bolton Wanderers 2-2 Portsmouth: Pompey survive some early scares before Ivan Klasnic opens the scoring for the Trotters with a header from Jack Wilshere's inviting left-wing cross
Owen Coyle's side double their lead on 28 minutes after a fine run and cross by Vladimir Weiss finds Kevin Davies who finishes well against their already relegated opponents
Instead of capitulating Portsmouth fight back and reduce the deficit in the 54th minute when Ivory Coast striker Aruna Dindane scores from Frederic Piquionne's pull-back
Dindane finds the back of the net again midway through the second half as Pompey show great character to cancel out Bolton's advantage
Hull City 0-1 Sunderland: The Tigers' increasingly slim hopes of avoiding relegation receive an early setback when Darren Bent taps the Mackems into a 1-0 lead
Iain Dowie's charges earn a great chance to equalise when Geovanni wins a penalty but Jimmy Bullard hits the post with his effort
There is more drama shortly before the interval when Jozy Altidore and Alan Hutton get into a scrap which results in both of them being sent off
Goals continue to elude Dowie's men in the second half and the 1-0 defeat leaves them requiring close to a miracle to avoid relegation
Wolverhampton Wanderers 1-1 Blackburn Rovers: The visitors make much the better start and take a deserved lead when Ryan Nelsen forces the ball home from a Morten Gamst Pedersen corner in the 28th minute
With the game into its final phase Wolves find an equaliser when last season's top scorer Sylvan Ebanks-Blake scores only his second of the campaign to earn them a point
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