Sam Williams climbed off the bench to grab a late goal and rescue a point for Brentford in the battle of the top two.
Bees striker Jordan Rhodes grabbed an early opener with a deflected shot, but John Akinde levelled with a header.
David Hunt's free-kick eluded everyone to restore the lead but Jose Mousinho's volley again drew Wycombe level.
Akinde's solo strike put Wycombe ahead for the first time but, after Tommy Doherty saw red for an elbow, Williams drilled in to snatch a draw late on.
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Brentford
: Hamer, Halls, Phillips, Bennett, Dickson (Johnson 45), Newton (Sam Williams 68), Bean, Hunt, Wood, MacDonald, Rhodes. Subs Not Used: Simon Brown, Smith, Osborne.
Booked : Bennett, Newton.
Goals : Rhodes 2, Hunt 22, Sam Williams 81.
Wycombe
: Stech, Akinde (Pittman 90), Casement, Johnson, Antwi, Woodman, Holt, Doherty, Mousinho (Phillips 45), Harrold, Spence, Phillips (Oliver 70). Subs Not Used: Ashton, Young.
Sent Off : Doherty (68).
Booked : Harrold, Mousinho, Antwi.
Goals : Akinde 15, Mousinho 40, Akinde 49.
Att : 10,642
Ref : Paul Taylor (Hertfordshire).
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