An acrobatic Anthony Thomas strike and a goal from Nicolau earned Barnet victory as Drewe Broughton and Simon Spender scored consolation goals for Wrexham.
This is deja vu for the Welshmen as Wrexham saved themselves from the dreaded drop into non-league oblivion on a dramatic final day of last season.
Five victories in their last six games ensured the Dragons' survival but the club were never, at any stage during last season's struggles, eight points adrift of safety as they are now.
But Little tried to rally his troops as he insisted: "I'm not a quitter and neither are my team so we'll keep fighting and do our best."
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