Wycombe held off a second-half fightback from bottom club Wrexham.
The visitors paid for two soft, early goals, keeper Gavin Ward's weak kick into the wind falling to Leon Knight who ran 20 yards before smashing home.
Another short Ward kick was headed by Dragons defender Carl Tremarco to Scott McGleish, who rounded Ward to score.
Michael Proctor pulled one back from a Tremarco free-kick, but Wrexham could not take advantage when Tommy Doherty was sent off for a second yellow card.
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