Matt Derbyshire made an immediate impact with two goals on his Wrexham debut after joining on a month's loan from Blackburn Rovers. The 19-year-old striker scored twice in the first half to increase the pressure on bottom-of-the-table Rushden.
Derbyshire had already troubled Rushden goalkeeper Scott Tynan before poking home Matt Crowell's left-wing cross.
The youngster's second was all his own work, driving forward and curling the ball into the top left of the net.
Wrexham: Ingham, Pejic, Danny Williams, Lawrence, Spender, Crowell (Mackin 89), Whitley, Mark Jones, Holt, Derbyshire, Sam Williams.
Subs Not Used: Michael Jones, Marc Williams, Done, Mike Williams.
Goals: Derbyshire 24, 36.
Rushden & D'monds: Tynan, Gier, Hatswell, Gulliver, Bull, Berry, Caskey, Stokes (Savage 55), Kelly, Broughton, Mikolanda (Tomlin 45).
Subs Not Used: Mills, Nicholls, Daniel Crane.
Booked: Bull, Tomlin, Gulliver.
Att: 3,195
Ref: L Mason (Lancashire).