Substitute Neil Harris struck a hat-trick as Millwall fought back to win.
David Forde stopped Hartlepool taking the lead when he saved Joel Porter's penalty after Tony Craig's handball.
But the hosts took control with Anthony Sweeney's two goals in three minutes, a sweet 25-yard volley followed by a neat finish from Porter's pass.
Harris' 10-minute hat-trick began with a 20-yard free-kick. He equalised from a tight angle before smashing in the winner after Sam Collins' mistake.
Hartlepool: Lee-Barrett, Collins, Nelson, Clark, Liddle, Humphreys, Jones, Sweeney, Monkhouse, Porter, Parker (Nardiello 70). Subs Not Used: Budtz, Robson, Foley, Mackay.
Booked: Sweeney.
Goals: Sweeney 23, 25.
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Millwall:
Forde, Whitbread, Duffy (Harris 45), Craig, Barron, Frampton, Henry (Martin 45), Laird, Bolder, Alexander, Grabban (Fuseini 70). Subs Not Used: Pidgeley, McLeod.
Booked: Frampton, Henry, Harris.
Goals: Harris 62, 67, 72.
Att: 3,601
Ref: Trevor Kettle (Rutland).
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