Colchester held promotion-chasing Scunthorpe to a goalless draw at the Weston Homes Community Stadium.
David Perkins and Kem Izzet both fired shots over the bar for the hosts, before Jimmy Walker foiled Iron striker Ben May after Garry Thompson's flick.
Colchester's Scott Vernon missed a fine chance before Marcus Williams hacked Clive Platt's effort away from danger.
The hosts' Steven Gillespie and Scunthorpe's Garry Hooper both dragged late chances wastefully wide.
Colchester: Walker, Maybury, Coyne, Baldwin, Tierney, Yeates, Hammond, Izzet (Jackson 65), Perkins (Wordsworth 80), Platt, Vernon (Gillespie 65).Subs Not Used: Gerken, White.
Booked: Yeates.
Scunthorpe: Murphy, Wright, Pearce, Byrne, Williams, Thompson (Morris 75), McCann, Togwell, Woolford (Hayes 88), May, Hooper.Subs Not Used: Lillis, Iriekpen, Lea.
Booked: Wright.
Att: 4,606.
Ref: Graham Horwood (Bedfordshire).
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