Northampton fought back superbly from three goals down early in the second half to earn a 4-4 draw.
Ben May's header and Gary Hooper's shot put the home side ahead before Scott McGleish pulled one back.
Hooper headed his 15th goal of the season for 3-1 and when May made it 4-1 on 51 minutes, it all looked finished.
Giles Coke's free-kick gave Northampton hope, Danny Jackman made it 4-3 and on 85 minutes keeper Joe Murphy fumbled Jackman's corner into his own net.
Scunthorpe: Murphy, Byrne, Iriekpen, Pearce, Williams, Sparrow, Togwell, Morris, Woolford, May, Hooper. Subs Not Used: Lillis, Thompson, Lea, Forte, Wright.
Booked: Sparrow, Togwell.
Goals: May 13, Hooper 19, 32, May 51.
Northampton: Dunn, Todd, Hughes (Holt 62), Crowe, Kyle Walker, Jackman, Coke, Osman, Davis, McGleish (Gilligan 69), Constantine. Subs Not Used: Zieler, Dolman, Larkin.
Goals: McGleish 24, Coke 53, Jackman 57, 85.
Att: 3,976
Ref: David Webb (Lancashire).
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