Southend booked their spot in the play-offs as Lee Barnard's last-minute goal saw them beat 10-man Carlisle and dent their automatic promotic hopes.
Charlie Mulgrew bent his free-kick over the wall to give the visitors the lead.
Carlisle levelled when Simon Hackney's free-kick deceived Darryl Flahavan in the Southend goal and went in.
Home defender David Raven was sent off for a late challenge on Nicky Bailey on 67 minutes before Barnard got the winner with a header from six yards.
Carlisle: Westwood, Raven, Livesey, Reid (Murphy 46), Horwood, Grant Smith (Madine 46), Lumsdon, Bridge-Wilkinson, Hackney, Dobie, Graham (Thirlwell 83). Subs Not Used: Howarth, Taylor.
Sent Off: Raven (67).
Booked: Bridge-Wilkinson.
Goals: Hackney 52.
Southend: Flahavan, Francis, Clarke, Barrett, Mulgrew, Black (Revell 80), McCormack, Bailey, Gower, Barnard, Walker. Subs Not Used: Collis, MacDonald, Moussa, Grant.
Booked: Bailey, Gower.
Goals: Mulgrew 7, Barnard 90.
Att: 9,122
Ref: Anthony Taylor (Greater Manchester).
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