Danny Graham scored twice as Carlisle hammered 10-man Gillingham. Peter Murphy gave Carlisle the lead with a low shot, before Garry Mulligan hit the bar for Gillingham, who then had Mark Bentley red-carded.
Luke Joyce headed home to make it 2-0, with Carlisle grabbing a third when Kevin Gall bundled in a cross.
Graham's first came from a penalty after Brent Sancho had fouled Johann Smith and a minute later he got his second with a close-range header.
Carlisle: Westwood, Raven, Livesey, Murphy, Aranalde, Thirlwell (Lumsdon 85), Joyce (Vipond 88), Jeff Smith, Graham, Gall, Holmes (Johann Smith 77).
Subs Not Used: Howard, Gray.
Booked: Joyce.
Goals: Murphy 14, Joyce 81, Gall 83, Graham 89 pen, 90.
Gillingham: Larrieu, Southall, Johnson, Sancho, Jackman, Tonge, Bentley, Bastians, Stone (Flynn 75), Mulligan, McDonald (Ndumbu-Nsungu 66).
Subs Not Used: Cox, Easton, Chorley.
Sent Off: Bentley (73).
Booked: Bentley, Johnson.
Att: 6,087.
Ref: M Dean (Wirral).