Grant frustrated the hosts when he somehow tipped Bradley Wright-Phillips' goalbound effort around the post.

The Owls also threatened, with Burton O'Brien testing Saints keeper Kelvin Davis and Richard Hinds heading over from the resulting corner.

Adam Hammill shot wide when well placed for Southampton and he was denied again by Grant from 18 yards before the end.

Southampton boss George Burley:
"It's disappointing to create so many chances and I felt we deserved to get the three points.

"Stern John has been magnificent for us recently and has scored some very good goals, but it wasn't his day.

"Bradley Wright-Phillips had some great chances to score as did others in the team, but unfortunately we couldn't take them."

Sheffield Wednesday boss Brian Laws on Saints looking for revenge after the Owls' 5-0 win last month:
"They are still smarting and I knew they would really come at us.

"I felt we dealt with that really well and got the ball down and played some nice football at times.

"We would always take a point from a difficult away trip when you have come so far on a Tuesday night."

Southampton: Davis, Wright, Bennett, Davies (Viafara 26), Skacel, Euell, Safri, Surman, Hammill (Lallana 74), John, Wright-Phillips (Saganowski 67).
Subs Not Used: Bialkowski, Rasiak.

Sheff Wed: Grant, Bullen, Hinds, Beevers, Spurr, Jermaine Johnson, Folly, Whelan, O'Brien, Small (Esajas 85), Sodje (Tudgay 28).
Subs Not Used: Burch, Lunt, Boden.

Booked: Whelan.

Att: 17,981.