Vaughan surgeon on knee injuries England under Trescothick

Vaughan, who missed the first Test and struggled through the last two games, saw a specialist on Monday.

"He has suffered intermittent pains which warrant further investigation, best done arthroscopically," said ECB medical officer Dr Peter Gregory.

Marcus Trescothick will captain the side, with Ian Bell staying on for the series, which begins on Saturday.

Vaughan will undergo the keyhole procedure at Sheffield's independent Thornbury Hospital on Friday.

It will be performed by top knee surgeon Derek Bickerstaff, who operated on him in 2001 and 2002.

Trescothick has captained England five times in limited-overs games in the past, winning three.

It's very difficult to lose the captain and a key player but Marcus Trescothick is a good captain and he has good men around him Ashley Giles

Bell has played in eight one-day internationals, with a top score of 75 on debut against Zimbabwe in Harare a year ago.

He is likely to have to battle with Vikram Solanki for Vaughan's place in the line-up.

Vaughan expressed his disappointment at not being able to play the five-match series in Pakistan.

But he is optimistic of recovering in time for England's next Test fixture, in India at the beginning of March.

"I'm bitterly disappointed to be missing the one-day matches against Pakistan but surgery really is the only option for me at the moment," he said.

"Hopefully I can make a full recovery in time for the tour to India in the early stages of next year."

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Vaughan has the sympathy of spinner Ashley Giles, who will undergo hip surgery on Wednesday after himself returning home early from Pakistan.

"With an all-year-round programme you can't help things like this," he said.

"It's the situation Vaughany is in and I am in; it's unfortunate it has happened at the same time.

"It's very difficult to lose the captain and a key player but Marcus Trescothick is a good captain and he has good men around him."